The series centers on Joey Tribbiani, who has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. After reuniting with his high-strung sister, Gina, a hairdresser, Joey moves in with his genius twenty-year-old nephew Michael, who is a rocket scientist. He begins a tentative romance with his superintendent, Alexis Garrett, and becomes close friends with fellow aspiring actor Zach Miller.